This will be an overly quick post. I am not a geneticist: I am a researcher patient who after having had ovarian cancer was put on multiple psychiatric drugs and got sicker and sicker. Due to Obama Care, I was finally able to get to a smart, food- based psych who immediately had me tested for MTHFR. I was positive to the most sensitive form, MTHFR c677t. MTHFR causes cancer, mental illness and heart disease. As a doctoral level researcher, I immediately began searching the web and found friends, great friends, who said I would have to have all 23 of my chromosomes tested as there could be other issues. And there were. I ended up training my doctor and still do today. I now teach epigenetics for wellness.
Inheriting some money, I was able to hire a genetic nutritionist who got me in great shape. One of the biggest issues for MTHFR is we have about a 70% reduced ability to detox. So an organic, non-gmo and supplements to balance mutations (snps or single nucleotide polymorphisms), gave me back my way of life and I felt great off of all the pharmecueticals that were full of excipients that I could not detox. The list is astonishing. (An interesting aside is that this means that our elders, often over medicated, just might be saved by genetic, now called epigenetic, testing of drugs.) I will let you look up excipients and simply say a lot of glypshosate is now showing up in many many meds.
At that time, 2014, 23&Me was the People’s Access to personal health information. It meant folks could choose natural holistic health treatments. In trying to control this move, away from big med and pharma, the FDA disallowed all medical info and if my story is correct, (check Wikipedia for a history) ancestry was what they could offer until Serling Hill developed an app that allowed raw genetic data to put into a nice neatly coded and colored form that natural practitioners could decode based on snpedia where researchers were rapidly adding evidence and treatments.
I will now jump forward in time.
Today, most practitioners, except for very specialisized geneticists, call themselves epigeneticists. This is because it is now understand WE ARE NOT OUR DNA and the ENVIRONMENT affects our health and can change DNA for good or bad. So if you are ill and work with an alternative or natruropathic nutritionist or other practioner, the first thing they SHOULD do is take a good old fashioned history that includes an extensive narrative of your life past and present. THEN geneticts will be considered.
I intend this highly complex topic to be as brief as possible. Pathways are how “stuff”, generally proteins, moves through our systems.
For all you need to know please study the Human Genome Progect, a still reputable research endeavor and never forget analyzing DNA is about probablities (because you have a mutation does not “prove” you will have an illness) and though we have 23 chromoses, the potential for mutations is almost endless and so now we have a highly competitive field for analysis that confuses many. BTW, you may have mutations that are real assests: I have one for longevity. Here is more than enough for your to understand pathways. https://www.genome.gov/27530687/
You do not need to be ill to be tested and use Sterling’s App. First, know that 23 & Me was sold to Genetech a traditional pharmeceutical firm, and they changed the mutations they test for and from what I hear, they continue to change them. Many well known practitioners no longer recommend them.
As big med fights to dominate, big alt med has also evolved. One millionare MTHFR naturopath posted a huge rant about this sale and is determined to 1. open his own lab and 2. work on just certain genes and snps, that he calls “dirty” and feels cause disease he is willing to treat, that he feels have been researched to his satisfaction. I doubt you will get the endocannobinoid pathway from him. And there are tons of competitors for your business. I make my choices based on history and ethics. The doctor I just mentioned is no longer seeing patients. He owns a vitamin firm, a genetic analysis system and maybe more. And there are some who believe that analysis can be done via computers, and that the diagnosis and treatment of illness can also be done via computers. One guy sees AI doing in diagnosing and treating in the future. I truly hope this does not happen. A good human practitioner I hope will never be replaced by a robot.
MTHFRSUPPORT, the company/partnership set up by Sterling’s App creator, Sterling HIll, has chosen another path. She has chosen Ancesty DNA as currently most suited for her amazing passion for discerning pathways. When you use her app, you get the pathways of other companies AND more, including your endocannabonid system. Thus you can see where you may be blocked and what type of cannabis, CBDs, THC or a combo may best suit your issues. AND updates are free. Here is their stance on the changes at 23 & Me: https://mthfrsupport.com/2017/08/the-new-v5-chip-from-23andme/
And here are MTHFRSUPPORT views, currently on the Endocannabinoid system: https://mthfrsupport.com/2017/06/the-endocannabinoid-system/
Illustration: From Collective Evolution.
So let’s say you are someone with any of the many, many illness that cannabis has shown to help. You can search the web for many of the claims or maybe you are someone who is just sick of the pharmecutical industry and its gouging and injuring and want natural medicine. Here is a list of possible diseases cannabis may treat from Europe listing 700 diseases: http://www.encod.org/info/700-MEDICINAL-USES-OF-CANNABIS.html
Let’s cut to the chase now. I recommennd Ancestry DNA for testing your saliva and Sterling’s App for discovering as many pathways as I believe anyone offers.
You are welcome to go to Amazon or any other company; the choices now are huge. I do not know if it will give you what is needed for Sterling’s App. I know no one else that offers the Endocannobonid pathways.
As you may have noticed my blogging system has changed and I am not up to speed but I felt this very basic issue was worth getting out asap. Thanks for reading and learning and here is to your wellness. Be sure to subscribe top right. Many thanks.